Prothena’s success is driven by our people. We are dedicated to attracting individuals who share our vision to improve human health by putting patients first.

But it’s not just about what we do at Prothena, it’s how we do it. That’s why we hire creative and courageous individuals who support one another and are not afraid to try new ideas. Our culture reflects our values which are brought to life every day by the following characteristics:

SELFLESS - Patients come first and we’re in this together. Our environment is collaborative and we measure success through our collective accomplishments.

COURAGEOUS - Transformational innovation leads to novel treatments. “Tried-and-true” won’t produce breakthroughs for patients – a pioneering spirit, willingness to accept certain risks and to try new approaches. Each Prothenian and functional team is expected to bring their heart, experience and trust on our journey.

IMAGINATIVE - We value and encourage a creative approach across all aspects of our work. We challenge ourselves and each other to think beyond what is known and approach our work through a lens of continuous improvement.

JOYFUL - Humor and heart allow us to tackle the seriousness of our work. Excellence and fun are not at odds – we love what we do and enjoy the journey.

Position Overview:

The Medical Director will support one or more development programs involving drug candidates in neuroscience. This role will focus on crafting and executing clinical trials in clinical development and work as a medical monitor for one or more studies. The Medical Director will be responsible for designing and executing development strategies as well as interpreting data from clinical studies.

Responsibilities:

• Serve as the primary medical point of contact for a project or study
• Lead medical monitoring while effectively performing and managing medical and safety reviews, processes, and projects for assigned compound development programs and clinical studies
• Contribute to the design, planning, and medical oversight of clinical trials for neurodegenerative disorders and provide clear and insightful clinical and scientific expertise to facilitate transition of assets from early clinical phase to late phase development
• Partner with Clinical Operations on the initiation and conduct of clinical trials, while interacting closely with other relevant functional areas in the preparation of clinical development plans, protocols, investigator brochures, clinical study reports, manuscripts and scientific presentations
• Interact in a proactive manner with CROs and other service providers to enhance communication between Prothena and third parties, including guidance to assess patient eligibility and ongoing protocol management
• Build and maintain collaborative relationships with investigators, thought leaders and sites across targeted disease area

Requirements:

Education and Experience:

• Medical Degree (MD) required – Neurologist preferred
• Board eligible or board certified with current medical license in US preferred
• 2+ years’ experience in clinical development and medical monitoring in biotech/pharmaceuticals
• 5+ years in clinical practice with experience in neurodegenerative diseases
• Proven experience working with clinical trials as an investigator/co-investigator
• Ability to understand complex scientific, clinical, biomarker-based, and statistical data and issues from an analytical standpoint
• Domestic and International travel as required

Competencies and Attributes:

• Demonstrated leadership to drive results that are needed to achieve company objectives in accord with Prothena’s culture and values – courageous, imaginative, selfless and joyful
• Excellent understanding of the clinical /pharmaceutical process to effectively communicate and provide required deliverables
• Exceptional leadership and team-building skills
• Ability to lead and influence, including strong problem-solving, conflict resolution, and analytical skills

Comp Overview:

The anticipated salary range for this role is $300,000 to $410,000. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. We may ultimately pay more or less than the posted range, and the range may be modified in the future. The final salary offered to a successful candidate will be dependent on several factors that may include – but are not limited to – the job final level offered, the type and length of experience within the job, type and length of experience within the industry, relevant education, qualifications, skills, certifications, performance, and business or organizational needs.

The hired applicant will be eligible to receive an annual bonus and an equity grant in the form of stock options.

Health & Wellness Overview:

• All Prothena employees (and their families) are covered by medical, dental and vision insurance, with Prothena paying ~90% of plan premiums.
• Prothena pays the full premium for basic life and disability insurance for all employees.
• Prothena employees are also eligible to enroll in our Company’s 401(k) plan, and are always 100% vested in their account balances.
• The 401(k) plan provides for a quarterly, non-discretionary, 3% company-paid contribution on eligible earnings, as well as an additional, annual discretionary Company match of up to 2% of eligible earnings.

New Prothena employees are also eligible for 17 days of paid vacation accrued over the course of the first year of employment, paid sick time in accordance with state law, and company-paid holidays.

More information about Prothena can be found at the Company’s website: www.prothena.com.